• Article  

      HIV-1 integrase: From biology to chemotherapeutics 

      Zeinalipour-Loizidou, E.; Nicolaou, Charalambos P.; Nicolaïdes, Andrew N.; Kostrikis, Leontios G. (2007)
      AIDS has claimed the lives of 25 million people worldwide, an additional 40 million people are HIV-infected and new cases are being diagnosed every year. Despite the fact that HAART has moved AIDS from the category of ...
    • Article  

      HIV-1 integrase: From biology to chemotherapeuticsAAA 

      Zeinalipour-Loizidou, E.; Nicolaou, Charalambos P.; Nicolaïdes, Andrew N.; Kostrikis, Leontios G. (2007)
      AIDS has claimed the lives of 25 million people worldwide, an additional 40 million people are HIV-infected and new cases are being diagnosed every year. Despite the fact that HAART has moved AIDS from the category of ...
    • Article  

      Synthesis of fused 1,2,4-dithiazines and 1,2,3,5-trithiazepines 

      Koyioni, Maria G.; Manoli, Maria; Koutentis, Panayiotis Andreas (2014)
      Reacting ( Z)-N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-1H-pyrazol-5-amines 5 with Et2NH and then with concd H2SO4 gives 5H-pyrazolo[3,4-e ][1,2,4]dithiazine-3-carbonitriles 7 in good yields (74-85%) and 6H-pyrazolo-[3,4 ...
    • Article  

      Use of real-time PCR and molecular beacons to detect virus replication in human immunodeficiency virus type 1-infected individuals on prolonged effective antiretroviral therapy 

      Lewin, S. R.; Vesanen, M.; Kostrikis, Leontios G.; Hurley, A.; Duran, M.; Zhang, L.; Ho, David D.; Markowitz, M.; Gibson, U. E.; Heid, C. A. (1999)
      We have designed a novel, precise, and sensitive assay to measure unspliced (US) human immunodeficiency virus type 1 (HIV-1) mRNA in peripheral blood mononuclear cells of HIV-1-infected individuals by using real-time PCR ...